Immunity

What is immunity? In this article we will delve deeper into the meaning of immunity. The defense system or immune system functions to defend the human body. The system provides protection against external and internal pathogens. All persons in this world have an immune system. This travels throughout the body. It occurs in the intestines, respiratory tract, blood, lymphatic system and skin.

What is immunity?

What is immunity? In this article we will delve deeper into the meaning of immunity. The defense system or immune system functions to defend the human body. The system provides protection against external and internal pathogens. All persons in this world have an immune system. This travels throughout the body. It occurs, among other things, in the intestines, respiratory tract, blood, lymphatic system and skin.

Although the immune system offers protection, things can sometimes go wrong. Things go wrong if an enemy manages to get in or if your own body is attacked by the immune system. The result is that it makes us sick. Doctors and research specialists want to do everything they can to combat a pathogen. The aim is that the cells in your own body will no longer be attacked.

Immunity exists when a person is not susceptible to a specific pathogen or disease. Natural immunity arises when people have contracted a particular disease. In such a situation, the person’s immune system will come into contact with the antigen or antigens of a pathogen. The body will then produce memory cells and antibodies against this. Consider, for example, babies who ingest antibodies by drinking breast milk. In addition to natural immunity, there is an artificial way to achieve immunity. Here too, a distinction can be made between passive and active immunization.

Protecting human body

Immune systems protect the body against unexpected invaders. These can be viruses, parasites and bacteria, for example. The body’s own cells with an abnormality are cleared up. Consider, for example, the clearing of tumor cells. It is difficult to distinguish between harmless substances and pathogens. This also applies to the body’s own cells that differ from a regular cell. Immune cells must choose whether to attack or accept. It is then important to find a good balance.

Invaders

From a practical technical point of view, things do not always go as they should. Enemies sometimes invade and create a disease. This can lead to unpleasant infectious diseases such as tuberculosis and malaria. Researchers do everything they can to prevent this. Special vaccines and remedies are made for this. These should ensure an immune response. A tumor cell is usually cleared away, but sometimes manages to escape.

Attackers

In diseases such as rheumatism or diabetes, the body’s own cells are attacked by the body’s own immune system. Then the system is much too offensive. Therapies have been developed that look at the causes of deficiencies in the immune system. People’s immune systems sometimes want to take action against pollen or dust mites. These are basically foreign substances, but can still lead to asthma and allergies. The immune system will then have to be made more tolerant. Studies are being conducted to learn from parasitic worms and stomach bacteria. Because these worms and bacteria protect themselves, the immune system is dampened.

Organ transplants

The immune system is also important in relation to organ transplants. Donor organs are always foreign to the body, which means they can be rejected by the immune system. This may mean that it is necessary for patients to use special medications. These can suppress the system.

What is herd immunity?

Herd immunity can be important to combat viruses and diseases. Vaccines are primarily used to protect you or your children. But it also creates group immunity. If more people have active immunity for a specific disease, the chance of spread becomes smaller. Measles is a good example of this. This condition can spread even if more than 5% of the population is not immune. Immunity is achieved by contracting the disease or being vaccinated.

Elimination of diseases

It’s quite simple. If a person can no longer get sick, the disease can no longer be transmitted to someone else. A disease can even disappear completely. Vaccinations can therefore ensure that diseases are eliminated. This has already happened with smallpox and there is hope that this will also happen with polio. It also applies to rubella and measles.

Protecting young children

Research shows that herd immunity protects young children. Young people who have not yet been vaccinated may benefit from herd immunity. This is also called herd immunity.

Passive immunization

There are two types of immunization: passive and active. During passive immunization, antibodies are administered. These substances are produced by animals or people and provide immediate protection against infectious diseases. If they are human, they are called immunoglobulins. In animal cases one speaks of antisera. The use of antisera can sometimes be associated with allergic reactions. That is why they have often been replaced by immunoglobulins of human origin.

Passive immunization is used to ward off or drastically reduce an infection. This form of protection is often used if a patient suffers from insufficient antibody formation. This may be a condition that developed at birth or may occur as a result of an illness.

Passive immunization is often used in the following situations:

  • In people at high risk of infection. This may be because a person has been exposed to specific microorganisms that cause the disease.
  • If a person has a high risk of serious complications. This can, for example, be the result of infections. Think of a young person who has leukemia and has been exposed to measles or chickenpox.
  • When there is too little time to provide sufficient protection through active immunization or when it is not available. This may be the case in the treatment to prevent a spider or snake bite.

Active immunization

When your immune system produces antibodies, memory cells are produced at the same time. This allows your body to respond quickly in the event of a new infection. This process is called active immunization.

Operation

There are two types of immunoglobulins that are used for passive immunization. We are talking about specific immunoglobulins and general human globulin.

General human globulin is produced from blood that comes from at least a thousand people who are donors. This ensures that many different antibodies are present. These substances prevent diseases such as measles, rubella, hepatitis A and others.

General human globulin is often used in a patient who does not have a properly functioning immune system. The immune system is then strengthened.

If it concerns passive immunization, special immunoglobulins are used for the immunization. The immunoglobulins arise from specific antibodies that exclusively protect against a specific disease. Examples of where immunoglobulins are currently used are in the fight against hepatitis B, rabies and tetanus. Antisera from an animal can be used to reduce the effect of toxins.

Results and side effects

Passive immunization has an immediate effect. It offers protection and takes effect immediately. The duration is for a short period of time. This does not provide protection over a longer period. This may have to be repeated.

Side effects

Normal human globulin causes a number of side effects. Consider, for example, fever, chills and general malaise. It may even happen that allergic reactions occur. General passive immunization sometimes disrupts responses to live viral vaccines. For this reason, it is not wise to carry out vaccinations three weeks before or after a vaccination with general human globulin.